Ahead of Time compiler for numeric kernels
Pythran is an ahead of time compiler for a subset of the Python language, with a focus on scientific computing. It takes a Python module annotated with a few interface description and turns it into a native Python module with the same interface, but (hopefully) faster.
It is meant to efficiently compile scientific programs, and takes advantage of multi-cores and SIMD instruction units.
Pythran supports Python 2.7 and also has a decent Python 3 support.