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Semi-elastic fiber optimisation in python.

Project description

SAENOPY: 3D Traction Force Microscopy with Python

DOC Coverage Status PyTest License: MIT

SAENOPY is a free open source 3D traction force microscopy (TFM) software. Its material model is especially well suited for tissue-mimicking and typically highly non-linear biopolymer matrices such as collagen, fibrin, or Matrigel.

It features a python package to use in scripts and an extensive graphical user interface.

Check out our Documentation on how to install and use it.

Installation

Standalone

To use saenopy without a complicated installation you can use our standalone binaries to get started right away.

Windows https://github.com/rgerum/saenopy/releases/download/v1.0.8/saenopy.exe

Linux https://github.com/rgerum/saenopy/releases/download/v1.0.8/saenopy

MacOS https://github.com/rgerum/saenopy/releases/download/v1.0.8/saenopy_mac.app.zip (in development..)

Using Python

If you are experienced with python or even want to use our Python API, you need to install saenopy as a python package. Saenopy can be installed directly using pip:

``pip install saenopy``

Now you can start the user interface with:

``saenopy``

Or by executing the script “gui_master.py” in your python interpreter.

Getting started

To get started you can have a look at our collection of example datasets.

Preprint

If you want to cite saenopy you can reference our article:

Dynamic traction force measurements of migrating immune cells in 3D biopolymer matrices
David Böhringer, Mar Cóndor, Lars Bischof, Tina Czerwinski, Niklas Gampl, Phuong Anh Ngo, Andreas Bauer, Caroline Voskens, Rocío López-Posadas, Kristian Franze, Silvia Budday, Christoph Mark, Ben Fabry, Richard Gerum
Nat. Phys. 20, 1816–1823 (2024); doi: https://doi.org/10.1038/s41567-024-02632-8

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