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Project description
SCARCCpy - Simulation of Combined Antibiotics in Cross-feeding Communities
SCARCC is a python package developed by the Harcombe Lab designed to identify synergistic interactions between antibiotics within our two-species cross-feeding microbial community.
This package utilizes COBRA to analyze the perturbation effects caused by antibiotics in the genome-scale metabolic network using Flux Balance Analysis (FBA), and COMETS simulations to incorporate multispecies growth simulation using Dynamic Flux Balance Analysis (dFBA).
Documentation
The documentation is at readthedocs
Installation
Python version greater than Python 3.10 is required.
Use pip to install, use of virtual environment is encouraged.
For more detail setting up in MSI, see INSTALL.rst
pip install scarcc
License
The SCARCC source code is available under the MIT License.
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