scicast: Single Cell Iterative Clustering and Statistical Testing. A package for interrogating single cell sequencing data.
Project description
scicast is a python utility that automates many of the repetitive steps of analyzing single cell sequencing data.
-k-means clustering to identify clusters
-Clustering and subclustering of data to identify ‘stable’ sets of cells.
-Statistical testing to identify top genes that indentify stable cluster.
-Correlation search and analysis to identify gene networks driving cluster identity.
-Outputs both plots for visualization (PCA and heatmap) cell and gene lists that can be used to refine analysis.