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scPCA - A probabilistic factor model for single-cell data

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scPCA is a versatile matrix factorisation framework designed to analyze single-cell data across diverse experimental designs.

scPCA schematic

scPCA is a young project and breaking changes are to be expected.

scPCA in a nutshell

scPCA enables the analysis of single-cell RNA-seq data across condtions. In simple words, it enables the incorporation of a design (model) matrix that encodes the experimental design of the dataset and infers how the gene loading weight vectors change from a specified reference condition to the treated condtion.

https://github.com/user-attachments/assets/182af56e-14e0-4357-ab31-1b392dd45d18

Quick install

scPCA makes use torch, pyro and anndata. We highly recommend to run scPCA on a GPU device.

Via Pypi

The easiest option to install scpca is via Pypi. Simply type

$ pip install scpca

into your shell and hit enter.

Credits

  • Harald Vöhringer

Release files for scpca 0.3.3

For a detailed explanation of source distributions (sdists) and built distributions (wheels), please see the package formats documentation.

Source distribution (sdist)

Source distribution for scpca 0.3.3
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Built distribution (wheel)

Table of built distributions (wheels) for scpca 0.3.3
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scpca-0.3.3-py3-none-any.whl Python 3 none any Details

Total release size: 75.1 kB

Release files / scpca-0.3.3.tar.gz

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0.3.3 This release

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0.3.1

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0.2.0

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0.1.0

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