A sovereign, local-first MCP server for High-Throughput Screening (HTS) assay calculations across Sub-Cellular, Cellular, Tissue, and Organism biological segments.
Project description
seosiri-bioassay-mcp
An open-source, local-first Model Context Protocol (MCP) server for High-Throughput Screening (HTS) assay calculations spanning Sub-Cellular, Cellular, Tissue, and Organism biological tiers.
💖 Sponsorship, B2B Custom Solutions & Attribution
👨💻 Lead Architect & Attribution
Designed and engineered by Momenul Ahmad, Lead Architect and Founder of SEOSiri.
🚀 Supported Biological Segments & Assays
- Sub-Cellular: TR-FRET ratio analysis for PROTAC (BRD4/CRBN), KRAS (G12C), receptor binding, and HICA ultra-sensitive protein assays.
- Cellular: UA-Glo luminescent screening for 2D/3D cell viability, Caspase 3/7 apoptosis, kinase activity, and reporter gene systems (NF-kB/Wnt).
- Tissue: 3D spheroid/organoid drug penetration depth and tissue slice barrier diffusion models.
- Organism: In vivo animal model pharmacokinetics ($C_{\max}$, AUC, half-life, plasma concentration decay).
Quickstart
pip install -e .
pytest tests/test_bioassay.py
🔌 Claude Desktop / Cursor Setup
Add this configuration to claude_desktop_config.json:
{
"mcpServers": {
"seosiri-bioassay": {
"command": "uv",
"args": [
"run",
"--github",
"SEOSiri-Official/bioassay-mcp",
"src/main_server.py"
]
}
}
}
License
Distributed under the MIT License. See LICENSE for details.
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