TROPPO - Tissue-specific RecOnstruction and Phenotype Prediction using Omics data
Project description
TROPPO
Troppo (Tissue-specific RecOnstruction and Phenotype Prediction using Omics data) is a Python package containing methods for tissue specific reconstruction to use with constraint-based models. The main purpose of this package is to provide an open-source framework which is both modular and flexible to be integrated with other packages, such as cobrapy, framed or cameo whose already provide generic data structures to interpret metabolic models.
A (MI)LP solver is required to use most of the present methods. The current methods support optlang, which in turn allow the use of solvers like CPLEX or Gurobi.
- The current methods implemented are:
FastCORE
CORDA
GIMME
(t)INIT
iMAT
- Methods to be implemented later:
MBA
mCADRE
PRIME
Documentation
Instalation from PyPI (stable releases)
pip install troppo
Instalation from github (latest development release)
pip install https://github.com/BioSystemsUM/troppo
Credits and License
Developed at the Centre of Biological Engineering, University of Minho
Released under the GNU Public License (version 3.0).
Project details
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