varsim 1.0.0

Variant Simulator

VarSim

VarSim generates simulations for all possible single nucleotide variants (SNVs) for the Matched Annotation from NCBI and EMBL-EBI (MANE) transcript, along with the corresponding protein using HGVS notation.

INSTALLATION

pip install varsim

Variation Simulation

cds("INS")

NM_000207.3:c.1A>G NP_000198.1:p.M1V NP_000198.1:p.Met1Val

NM_000207.3:c.2T>G NP_000198.1:p.M1R NP_000198.1:p.Met1Arg

M_000207.3:c.2T>A NP_000198.1:p.M1K NP_000198.1:p.Met1Lys

NM_000207.3:c.3G>A NP_000198.1:p.M1I NP_000198.1:p.Met1Ile

NM_000207.3:c.1A>T NP_000198.1:p.M1L NP_000198.1:p.Met1Leu

... ... ... ...

NM_000207.3:c.328A>T NP_000198.1:p.N110Y NP_000198.1:p.Asn110Tyr

NM_000207.3:c.329A>T NP_000198.1:p.N110I NP_000198.1:p.Asn110Ile

NM_000207.3:c.330C>T NP_000198.1:p.N110= NP_000198.1:p.Asn110=

NM_000207.3:c.328A>C NP_000198.1:p.N110H NP_000198.1:p.Asn110His

NM_000207.3:c.329A>C NP_000198.1:p.N110T NP_000198.1:p.Asn110Thr

utr5("INS")

NM_000207.3:c.-59A>G

NM_000207.3:c.-59A>T

NM_000207.3:c.-59A>C

NM_000207.3:c.-58G>A

NM_000207.3:c.-58G>T

... ... ... ...

NM_000207.3:c.-2C>A

NM_000207.3:c.-2C>T

NM_000207.3:c.-1C>G

NM_000207.3:c.-1C>A

NM_000207.3:c.-1C>T

utr3("INS")

NM_000207.3:c.*1A>G

NM_000207.3:c.*1A>T

NM_000207.3:c.*1A>C

NM_000207.3:c.*2C>G

NM_000207.3:c.*2C>A

... ... ... ...

NM_000207.3:c.*72G>T

NM_000207.3:c.*72G>C

NM_000207.3:c.*73C>G

NM_000207.3:c.*73C>A

NM_000207.3:c.*73C>T

splicing("INS")

NM_000207.3:c.187+2T>

NM_000207.3:c.188-2A>G

NM_000207.3:c.187+1G>A

NM_000207.3:c.187+2T>A

NM_000207.3:c.188-1G>A

NM_000207.3:c.187+1G>T

NM_000207.3:c.188-2A>T

NM_000207.3:c.188-1G>T

NM_000207.3:c.187+1G>C

NM_000207.3:c.187+2T>C

NM_000207.3:c.188-2A>C

NM_000207.3:c.188-1G>C