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ZipStrain

ZipStrain is a strain-resolution metagenomics toolkit for profiling mapped reads into nucleotide-count tables and comparing samples at genome and gene resolution.

Documentation:

Install

Base install:

pip install zipstrain

Experimental matrix utilities with Torch-backed execution:

pip install "zipstrain[matrix]"

Notes:

  • Apple Silicon can use the standard torch wheel with the MPS backend.

  • Linux CUDA installs should replace Torch with the matching CUDA wheel from PyTorch:

    pip install "zipstrain[matrix]"
    pip install --upgrade torch --index-url https://download.pytorch.org/whl/cu124
    
  • Profiling requires samtools to be installed separately when using pip.

Verify

zipstrain --version
zipstrain test

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