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DILImap is a pioneering toxicogenomics atlas purpose-built for modeling Drug-Induced Liver Injury (DILI). It features RNA-seq profiles from primary human hepatocytes exposed to 300 diverse compounds. It offers a powerful foundation for mechanistic insight and predictive modeling.

ToxPredictor, trained on DILImap, sets a new benchmark in DILI risk assessment. With 88% sensitivity at 100% specificity, it outperforms traditional methods and reliably flags even the most elusive DILI-prone drugs, including withdrawn and idiosyncratic compounds.

Publication: Bergen et al. (2025)

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Usage & Support

  • Installation: Install using pip install dilimap

  • Documentation & Notebooks: Visit dilimap.org for detailed usage instructions and reproducibility notebooks.

  • Support: Reach out at DILImap@cellarity.com with any questions or feedback.

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Release files for DILImap 1.0.5

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