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biocognia-markers

The marker graph that SCIMAP Pro, Plexora and other BioCognia products share.

  • Nodes: markers and cell families.
  • Edges: what is known about them: exceptions, exclusions, subsets, carriers and co-expression.
  • Evidence: the evidence behind each node and edge.
  • Verification: an item counts as verified only when a machine has found every part of it in its source (biocognia-markers verify).
import biocognia_markers as bm

graph = bm.load()                       # the shipped graph, with the user's overlay laid over it
graph.resolve(["CD3e", "PD-1"])
graph.edges_of("m:pd1")

To add to the graph, an agent follows the skill biocognia-marker-graph (src/biocognia_markers/skills/marker-graph/SKILL.md). tools/migrate.py built the first graph from SCIMAP Pro's rule library and Plexora's vocabulary. Where those two sources disagree is listed in MIGRATION_REPORT.md.

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