Cosmos: A Position-Resolution Causal Model for Direct and Indirect Effects in Protein Functions
Project description
Cosmos
Update
v1.0: July 15, 2025
- Initial Version of Cosmos
Overview
Cosmos is a python package for multi-phenotype deep mutational scanning analysis. Specifically, it is suitable for two sequential protein functional phenotypes, one upstream and one downstream - for example, abundance and acitivity.
Installation
Cosmos uses Poetry for environment and dependency management.
To install Cosmos, follow these steps:
- Install Poetry (if not already installed). Please follow the guideline on Poetry's official documentation.
- Clone the repository.
git clone https://github.com/Coyote-Maestas-Lab/cosmos.git
cd cosmos
- Install and activate the environment.
poetry lock
poetry install
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