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CUDA-accelerated CRISPR off-target search

Project description

crispr

CUDA-accelerated CRISPR off-target search with MIT/CFD scoring. Includes a C++ core, CUDA kernels, CLI, and Python bindings.

Features:

  • GPU/CPU parity for Hamming, MIT, CFD scoring (configurable via JSON tables).
  • Build/load genome indexes; score guides with NGG/SpCas9 (20nt) v0.1.0 scope.
  • CLI (crispr-gpu) and Python API (import crispr_gpu as cg).

Install:

pip install crispr

Source/build: see https://github.com/omniscoder/crispr-gpu

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