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gnt

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Python package for identifying Genetic iNTeractions from combinatorial screening data.

Tutorial

To install:

$ pip install gnt

Basic command line usage

$ gnt "https://raw.githubusercontent.com/PeterDeWeirdt/bigpapi/master/data/processed/bigpapi_lfcs.csv" example_output --control CD81 --control "HPRT intron"

Basic python usage

import gnt
import pandas as pd
lfcs = pd.read_csv('https://raw.githubusercontent.com/PeterDeWeirdt/bigpapi/master/data/processed/bigpapi_lfcs.csv')
guide_residuals, model_info = gnt.get_guide_residuals(lfcs, ['CD81', 'HPRT intron'], scale=True)
gene_scores = gnt.get_gene_residuals(guide_residuals, 'scaled_residual_z')

TODO

Credits

This package was created with Cookiecutter and the audreyr/cookiecutter-pypackage project template.

History

0.1.0 (2020-06-29)

  • First release on PyPI.

0.1.1 (2020-07-09)

  • Automated release

0.1.2 (2020-07-09)

  • Travis bug fix

0.2.0 (2020-07-13)

  • Add columns to guide and gene output for base LFC of pairs

  • Check inputs, removing guides without the right number of pairs or control pairs

Release files for gnt 0.2.0

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