mhctyper 0.1.5

MHC Class I and II typer based on polysolver algorithm.

mhctyper

Polars-accelerated MHC class I and II typing based on Polysolver algorithm.

Features

• Supports both class I and II typing with good accuracy
• Runtime speedup boosted by polars
• Minimum I/O operations
• Easy integration to workflow/pipeline with better CLI and proper packaging.

Installation

mhctyper can be installed from PyPI:

pip install mhctyper

Quick start

mhctyper simply requires 2 inputs:

• Alignment to HLA alleles in BAM format: $bam.
• Population frequency from the original polysolver: HLA_FREQ.txt.

mhctyper --bam "$bam" \
    --freq "HLA_FREQ.txt" \
    --outdir "$outdir" \
    --nproc 8

Please refer to documentation for more details.