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Small django app to model genes

Project description

# phizz-genes #

A small django app to represent genes, transcripts, omim phenotypes, aliases etc

## Instructions ##

- Add phizz-genes to your INSTALLED_APPS settings like:


- Run `python migrate` to create the models

## Models ##

class Gene(models.Model):

#The ensembl gene id, ex. 'ENSG00000156110'
#can be use with link like:
ensembl_id = models.CharField(max_length=20)

chrom = models.CharField(max_length=30)
start = models.IntegerField()
stop = models.IntegerField()

#The hgnc symbol, ex. 'ADK
hgnc_symbol = models.CharField(max_length=20, blank=True)

description = models.CharField(max_length=200, null=True)
#The hgnc id, ex. '257' for using link like:
hgnc_id = models.IntegerField(null=True)

#entrez id, ex. 132, for using link like:
entrez_id = models.IntegerField(null=True)

#vega id, ex. OTTHUMG00000018506, for using link like:
vega_id = models.CharField(max_length=20, null=True)

#ucsc id, ex. uc001jwi.4, for using link like:
ucsc_id = models.CharField(max_length=20, null=True)

#pli_score is the estimated sensibility to lof mutations estimated by ExAC
pli_score = models.DecimalField(max_digits=6, decimal_places=5, null=True)

def __str__(self):
return self.hgnc_symbol

#One gene can have several transcripts, one transcript are attached to one gene
class Transcript(models.Model):
gene = models.ForeignKey(Gene, on_delete=models.CASCADE)
refseq_name = models.CharField(max_length=30, null=True)
ensembl_transcript_id = models.CharField(max_length=30)

def __str__(self):
return self.refseq_name

#One phenotype can have several transcripts, one transcript are attached to one gene
class Omim(models.Model):
gene = models.ForeignKey(Gene, on_delete=models.CASCADE)
omim_id = models.IntegerField()

class Alias(models.Model):
gene = models.ForeignKey(Gene, on_delete=models.CASCADE)
alias = models.CharField(max_length=20)

class UniProt(models.Model):
gene = models.ForeignKey(Gene, on_delete=models.CASCADE)
uniprot_id = models.CharField(max_length=20)

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