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sc2ts

Sc2ts stands for "SARS-CoV-2 tree sequence" (pronounced "scoots" optionally) and consists of

  1. A method to infer Ancestral Recombination Graphs (ARGs) from SARS-CoV-2 genome sequence data at pandemic scale.
  2. A lightweight wrapper around tskit Python APIs specialised for the output of sc2ts which enables efficient node metadata access.
  3. A lightweight wrapper around Zarr Python which enables convenient and efficient access to the full Viridian dataset (alignments and metadata) in a single file using the VCF Zarr specification.

For details on the software, please see the online documentation. For information on the method and an inferred ARG, please see this preprint:

Shing H. Zhan, Yan Wong, Anastasia Ignatieva, Katherine Eaton, Isobel Guthrie, Benjamin Jeffery, Duncan S. Palmer, Carmen Lia Murall, Sarah P. Otto, and Jerome Kelleher (2025) A Pandemic-Scale Ancestral Recombination Graph for SARS-CoV-2. bioRxiv: 2023.06.08.544212; doi: https://doi.org/10.1101/2023.06.08.544212

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Release files for sc2ts 1.1.0

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Source distribution for sc2ts 1.1.0
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sc2ts-1.1.0.tar.gz 1.9 MB Details

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Table of built distributions (wheels) for sc2ts 1.1.0
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sc2ts-1.1.0-py3-none-any.whl Python 3 none any Details

Total release size: 2.1 MB

Release files / sc2ts-1.1.0.tar.gz

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Release files / sc2ts-1.1.0-py3-none-any.whl

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1.1.0 This release

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1.0.0

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0.0.3

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