msprime

Last released May 20, 2026

Simulate genealogical trees and genomic sequence data using population genetic models

tskit

Last released May 14, 2026

The tree sequence toolkit.

bio2zarr

Last released Apr 15, 2026

Convert bioinformatics data to Zarr

pyslim

Last released Mar 6, 2026

Manipulate tree sequences produced by SLiM.

tscompare

Last released Mar 6, 2026

Tools for comparing tree sequences.

tsbrowse

Last released Mar 5, 2026

Webapp to view and visualise the information structure in tskit ARGs

tsinfer

Last released Mar 5, 2026

Infer tree sequences from genetic variation data.

sc2ts

Last released Mar 5, 2026

Infer ARGs for SARS-Cov2 in tskit format

tszip

Last released Mar 5, 2026

Compression utilities for tree sequences

tstrait

Last released Mar 3, 2026

Quantitative trait simulation of tree sequence data

kastore

Last released Mar 3, 2026

A write-once-read-many store for simple numerical data

vcztools

Last released Mar 2, 2026

Implementation of bcftools for VCF Zarr

stdpopsim

Last released Mar 19, 2025

A library of population genetic simulation models

lshmm

Last released Jun 24, 2024

None

wormtable

Last released Oct 5, 2023

Write-once read-many data sets using Berkeley DB.

demes

Last released May 4, 2023

tools for describing demographic models

htsget

Last released Nov 7, 2022

Python API and command line interface for the GA4GH htsget API.

phylokit

Last released May 21, 2022

"Experimental, do not use!"

kingman

Last released Jun 1, 2015

An example Python package to simulate Kingman's coalescent

discsim

Last released Jan 2, 2015

Efficient coalescent simulation in continuous space

ercs

Last released Jan 30, 2013

Coalescent simulations in continuous space