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A causality-aware model for disentangling treatment effects at single-cell resolution for perturbational scRNA-seq data

Project description

scCausalVI - a causal variation inference model for scRNA-seq

Introduction

scCausalVI is a causality-aware model for analyzing single-cell RNA sequencing data, designed to disentangle treatment effects from intrinsic cellular heterogeneity. Using a deep generative framework, scCausalVI enables precise, single-cell-level inference of gene expression responses to experimental treatments by modeling the causal dependencies between treatment effects and cellular states. Key features include support for clustering, treatment response analysis, and counterfactual inference, allowing users to explore cellular variability and identify treatment-responsive subpopulations.

Installation

To install the latest version of scCausalVI via pip:

pip install scCausalVI

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