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SpaMosaic: Mosaic Integration of Spatial Multi-omics using GNNs and Contrastive Learning

Reason this release was yanked:

wrong dependence

Project description

SpaMosaic

SpaMosaic is a Python package for spatial multi-omics data integration using contrastive learning and graph neural networks. It supports integration of partially overlapping modalities and facilitates downstream analyses such as spatial domain identification and modality imputation.


🔧 Features

  • Horizontal integration: integrates multiple slices within a single modality
  • Vertical integration: integrates multiple modalities measured from the same slice
  • Mosaic integration: integrates multiple slices with overallping modalities
  • Imputation: imputes expression profiles of missing omics

🚀 Installation

We recommend using Python 3.8+ and a Conda environment:

pip install spamosaic

📚 Documentation

📖 Full tutorials and API reference: 👉 https://spamosaic.readthedocs.io

📄 License

SpaMosaic is released under the MIT License. © 2025 Jinmiao Lab

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