cnc-4-science

Python control library for low-cost, easy-to-assemble, open-source GRBL CNC routers used as the gantry for scientific automation — liquid handling, pick-and-place, fraction collection, anything that fits the pattern "move this tool to that well and do something."

Reference hardware is the Genmitsu 3018-PROVer V2, but the library is GRBL-generic.

Full docs, hardware build guides, and end-to-end example projects (liquid handling, vacuum pick-and-place) live on GitHub: https://github.com/AccelerationConsortium/cnc-4-science.

Install

pip install cnc-4-science

Python 3.9+.

API at a glance

Public surface is exported from cnc_machine_core:

from cnc_machine_core import CNC_Machine, Deck, DeckState

CNC_Machine — motion + spindle

Deck + Labware — coordinate resolution

from cnc_machine_core import Deck
from opentrons_shared_data.labware import load_definition

deck = Deck("cnc_4_slot_deck")   # built-in: 4-slot, sized for the Genmitsu 3018
# deck = Deck("cnc_1_slot_deck")   # built-in: open / single slot
# deck = Deck("path/to/my_deck.json")  # custom JSON

# Standard SBS labware by Opentrons load name:
plate = deck.load_labware_definition(
    "1", load_definition("corning_96_wellplate_360ul_flat", 1)
)

# Or a custom JSON for non-SBS gear:
# plate = deck.load_labware("1", "custom_labware/my_rack.json")

x, y, z = plate["A1"].position()                       # absolute machine coordinates
x, y, z = plate["A1"].position(offset=tool.offset)     # apply tool's XY/Z mount offset

There is no default deck — pass an explicit name (or path) so the CNC footprint is visible at the call site.

DeckState — per-well status tracking

from cnc_machine_core import DeckState

ds = DeckState()
ds.init_wells_from_labware("1", plate)
ds.init_from_preset({"1": {"A1": "sample"}})
ds.set_status("1", "A1", "processed")        # auto-saves to YAML
loc = ds.find_next(["1", "2"], "sample")     # ("1", "A2")
ds.count(["1"], "processed")
ds.summary()

Status strings are application-defined.

Minimal config

cnc_config.yaml:

cnc:
  com_port: COM4          # Windows: COMx | macOS: /dev/tty.usbserial-* | Linux: /dev/ttyUSB0
  baud_rate: 115200
  bounds:
    x: [0, 280]
    y: [0, 180]
    z: [-37, 0]

virtual: false            # true = dry-run; log G-code only, no hardware

bounds: must match your physical CNC envelope; the shipped values are for the Genmitsu 3018.

License

GNU General Public License v3.0 or later.