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cytozip: index-free, chunk-compressed storage for scalable single-cell DNA methylation analysis

A scalable, cloud-native ecosystem for single-cell and population DNA methylation analysis

Installation

pip

# Prerequisites (one of):
#   conda install -c bioconda htslib libdeflate          # recommended
#   apt-get install libhts-dev libdeflate-dev            # Debian/Ubuntu
#   brew install htslib libdeflate                       # macOS
pip install cytozip
# or reinstall
pip uninstall -y cytozip && pip install git+http://github.com/DingWB/cytozip

conda (To-DO)

# (when published to bioconda)
conda install -c bioconda -c conda-forge cytozip

Implementation

allcools ballcools cytozip
Format .tsv.gz .ballc .cz
Compression algorithm bgzip bgzip cytozip
Support Random Access ? Yes Yes Yes
Need extra index file for query? Yes yes No
Quickly Merge? No No Yes

img.png

Usage

Documentation

Example dataset

https://figshare.com/articles/dataset/cytozip_example_data/25374073

Download files

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Source Distribution

cytozip-0.3.tar.gz (690.1 kB view details)

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0.3.9

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