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Structure Ensemble Inference by Sequencing, Mutation Identification, and Clustering of RNA (SEISMIC-RNA)

Project description

SEISMIC-RNA

Structure Ensemble Inference by Sequencing, Mutation Identification, and Clustering of RNA

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About

SEISMIC-RNA analyzes data from RNA mutational profiling experiments, such as DMS-MaPseq and SHAPE-MaP. This software introduces an optimized implementation of the algorithm DREEM for detecting and quantifying RNA structure ensembles.

Installation and Usage

Documentation for installing and using SEISMIC-RNA is available on GitHub Pages.

Issues

The issue page of the GitHub repository is the official location for reporting bugs and other issues. Before opening a new issue, please check if a similar issue already exists.

Contributors

SEISMIC-RNA has been developed by the following individuals in the lab of Silvi Rouskin at Harvard Medical School:

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