A flexible and fast mixed model toolbox.
Project description
Limix is a flexible and efficient linear mixed model library with interfaces to Python. Genomic analyses require flexible models that can be adapted to the needs of the user. Limix is smart about how particular models are fitted to save computational cost.
LATEST: iSet, interaction set tests for gene-context interactions, is now in Limix.
Installation
Using Conda package manager
Conda is a package manager designed for Python and R users/developers of scientific tools, and comes with the Anaconda distribution. Currently we support this installation for Linux 64 bits and OSX operating systems.
conda install -c https://conda.anaconda.org/horta limix
Using Pip
If you don’t have Conda (or don’t want to use the above method), Limix can be installed via Pip package manager.
pip install limix
This approach is not as straightforward as the first one because it requires compilation of C/C++ and (potentially) Fortran code, and some understanding of dependency resolution is likely to be required. We provide bellow recipes for some popular Limix distributions, assuming you have the wget command line tool.
Ubuntu
bash <(wget -O - https://raw.githubusercontent.com/PMBio/limix/master/deploy/apt_limix_install)
Fedora
bash <(wget -O - https://raw.githubusercontent.com/PMBio/limix/master/deploy/dnf_limix_install)
OpenSUSE
bash <(wget -O - https://raw.githubusercontent.com/PMBio/limix/master/deploy/zypper_limix_install)
From source
This is more tricky in terms of dependency resolution but useful for developers.
git clone https://github.com/PMBio/limix.git cd limix python setup.py install # or python setup.py develop
Usage
A good starting point is our package Vignettes. These tutorials are available from this repository: https://github.com/PMBio/limix-tutorials.
The main package vignette can also be viewed using the ipython notebook viewer: http://nbviewer.ipython.org/github/pmbio/limix-tutorials/blob/master/index.ipynb.
Alternatively, the source file is available in the separate Limix tutorial repository: https://github.com/PMBio/limix-tutorials
Problems
If you want to use Limix and encounter any issues, please contact us via limix@mixed-models.org.
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